
BENEFITS
Nourishing body moisturizer and targeted treatment for thin, crepey skin
Smooth texture
Improves the root cause of crepey skin by supporting epidermal thickness for a firmer look and feel.01
Deep hydration
Replenishes and locks in hydration to keep skin soft, plump, and nourished.01
Barrier support
Fortifies the skin barrier to protect against daily stressors and moisture loss.01
5-STAR REVIEWS
See why customers love OS-01 BODY
“The skin on my legs was starting to look older—dry and crepey—at 46. After just a few weeks, it now looks plump and youthful, like it did 10 years ago.” – Jen A.
“OS-01 Body has been a game changer. Within a few weeks, I noticed a remarkable improvement in my skin’s quality, and it continues to get better with daily use. My skin now looks tighter, less dry, and the texture has almost returned to how it was before menopause—more hydrated and fresh. Science matters, and OneSkin truly got the science right.” – Tia T.
“I love this body lotion. My crepey skin is transforming. I wish I had taken photos before starting because I had tried so many products with no results that I didn’t expect this one to be any different. I was so wrong. I’m hoping it will eventually fade all of my dark spots. I’m a customer for life...” – Myra P.
The proof is in the pictures
The Science Behind OS-01 BODY
Your skin is your largest organ and plays a vital role in your overall health as you age. Over time, it becomes thinner, more fragile, and less effective at protecting you from external aggressors. While most skincare focuses on the face, the other 97% of your skin is just as essential for longevity and well-being. OS-01 BODY is designed to strengthen your skin barrier from the neck down, keeping it resilient.
To evaluate OS-01 BODY’s effectiveness, our scientists measured epidermal thickness—a key indicator of barrier strength—using human skin samples in the lab. Results showed a 40% increase in epidermal thickness compared to untreated skin. This aligns with clinical findings demonstrating OS-01 BODY enhances skin barrier function by up to 41.49%.01
Shown in lab studies on ex vivo human skin samples by measuring epidermal thickness of histology images. Skin treated with OS-01 BODY displayed a significant average increase of +40% compared to skin with no treatment. Data was measured in triplicate.
Getting started with OS-01 BODY
Follow these easy steps for optimal results
- Apply to arms, legs, chest, back, and stomach
- Massage until absorbed
- Use 2 times daily
Customer reviews
❓ Frequently Asked Questions
Targets the Root Cause of Skin Aging
Targets the Root Cause of Skin Aging
OS-01 BODY doesn’t just mask signs of aging — it addresses one of its root causes: cellular senescence. By helping reduce the number of damaged, aging cells, it supports healthier, more efficient skin renewal from within.
Full-Body Benefits, Head to Toe
Full-Body Benefits, Head to Toe
Designed for arms, legs, chest, back, and torso, this formula brings facial-level science to the rest of your body. Anywhere your skin needs firmness, smoothness, or hydrating repair, OS-01 BODY delivers targeted support.
Lightweight Feel, Long-Lasting Results
Lightweight Feel, Long-Lasting Results
The silky, fast-absorbing texture melts into the skin without residue, making it perfect for daily use. Despite its light feel, it provides deep, long-lasting moisture and continuous barrier-strengthening benefits.
Backed by Over 5 Years of Research
Backed by Over 5 Years of Research
OS-01 BODY is the result of extensive R&D, screening more than 900 peptides to find one that effectively reverses biological skin aging. Every bottle embodies years of scientific rigor and a commitment to skin longevity.
Complements Any Skincare Routine
Complements Any Skincare Routine
Whether your routine is simple or advanced, OS-01 BODY fits seamlessly. Use it alone or layer it with your favorite body moisturizers — its peptide-driven benefits work independently to enhance your skin’s overall health.

