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OneSkin BODY OS-01 Peptide Topical Supplement & Skin Longevity Age Reversal Moisturizer | Safe for Sensitive Skin, Fragrance-Free

OneSkin BODY OS-01 Peptide Topical Supplement & Skin Longevity Age Reversal Moisturizer | Safe for Sensitive Skin, Fragrance-Free

 (6,489 Reviews)
Regular price $88.90
Regular price $88.90 Sale price $105.90
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OneSkin BODY OS-01 Peptide Topical Supplement & Skin Longevity Age Reversal Moisturizer | Safe for Sensitive Skin, Fragrance-Free
Regular price $88.90
Regular price $88.90 Sale price $105.90
SAVE 16% Sold out

Science-Backed Body Care

Powered by the patented OS-01 peptide, OS-01 BODY targets aging at the cellular level — not just the surface. It strengthens the skin barrier, boosts hydration, and promotes smoother, firmer, more resilient skin from the neck down. It’s advanced body care rooted in real science.

Clinically Proven Skin Renewal

In clinical studies, OS-01 BODY increased epidermal thickness by up to 40%, a key marker of healthier skin. With consistent use, it improves texture, enhances elasticity, and supports long-term skin longevity. Visible results meet measurable science.

Daily Hydration + Barrier Support

This lightweight, fast-absorbing formula delivers deep hydration while reinforcing your skin’s natural defense system. It locks in moisture without heaviness, leaving skin soft, supple, and protected throughout the day.

Gentle, Clean, and Dermatologist-Tested

Formulated for even the most sensitive skin, OS-01 BODY is fragrance-free and free from parabens, sulfates, silicones, and unnecessary additives. It’s designed to nourish and repair without irritation — just pure, effective skincare.

A Longevity Ritual for Your Skin

More than a lotion, OS-01 BODY is a long-term investment in your skin’s health. By reducing the burden of senescent cells, it helps your skin function younger for longer, supporting a stronger, smoother, more youthful appearance as you age.

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    BENEFITS

    Nourishing body moisturizer and targeted treatment for thin, crepey skin

    Smooth texture

    Improves the root cause of crepey skin by supporting epidermal thickness for a firmer look and feel.01

    Deep hydration

    Replenishes and locks in hydration to keep skin soft, plump, and nourished.01

    Barrier support

    Fortifies the skin barrier to protect against daily stressors and moisture loss.01

    5-STAR REVIEWS

    See why customers love OS-01 BODY

    “The skin on my legs was starting to look older—dry and crepey—at 46. After just a few weeks, it now looks plump and youthful, like it did 10 years ago.” – Jen A.

    “OS-01 Body has been a game changer. Within a few weeks, I noticed a remarkable improvement in my skin’s quality, and it continues to get better with daily use. My skin now looks tighter, less dry, and the texture has almost returned to how it was before menopause—more hydrated and fresh. Science matters, and OneSkin truly got the science right.” – Tia T.

    “I love this body lotion. My crepey skin is transforming. I wish I had taken photos before starting because I had tried so many products with no results that I didn’t expect this one to be any different. I was so wrong. I’m hoping it will eventually fade all of my dark spots. I’m a customer for life...” – Myra P.

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      The Science Behind OS-01 BODY

      Your skin is your largest organ and plays a vital role in your overall health as you age. Over time, it becomes thinner, more fragile, and less effective at protecting you from external aggressors. While most skincare focuses on the face, the other 97% of your skin is just as essential for longevity and well-being. OS-01 BODY is designed to strengthen your skin barrier from the neck down, keeping it resilient.

      To evaluate OS-01 BODY’s effectiveness, our scientists measured epidermal thickness—a key indicator of barrier strength—using human skin samples in the lab. Results showed a 40% increase in epidermal thickness compared to untreated skin. This aligns with clinical findings demonstrating OS-01 BODY enhances skin barrier function by up to 41.49%.01

      Shown in lab studies on ex vivo human skin samples by measuring epidermal thickness of histology images. Skin treated with OS-01 BODY displayed a significant average increase of +40% compared to skin with no treatment. Data was measured in triplicate.

      Getting started with OS-01 BODY

      Follow these easy steps for optimal results

      • Apply to arms, legs, chest, back, and stomach
      • Massage until absorbed
      • Use 2 times daily
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        How it works

        Powered by the OS-01 Senescence Blocking Peptide™

        The first and only peptide scientifically proven to reverse skin’s biological age.02,03

      • Lynn S.

        only been using a little over a week. Will review after I have finished using the bottle.

        Verified Buyer 

      • Alexia F.

        The only cream that actually works to revive crepy skin. I do still need to use an oil on top to lock in the moisture but this is by far the best results I have had

        Verified Buyer 

      • mary

        I like the lotion. I'm waiting to see the results. It's expensive. Hope it's worth it. I tend to get orders mixed up. It's a good thing Customer service is great.

        Verified Buyer 

        ❓ Frequently Asked Questions

        Targets the Root Cause of Skin Aging

        OS-01 BODY doesn’t just mask signs of aging — it addresses one of its root causes: cellular senescence. By helping reduce the number of damaged, aging cells, it supports healthier, more efficient skin renewal from within.

        Full-Body Benefits, Head to Toe

        Designed for arms, legs, chest, back, and torso, this formula brings facial-level science to the rest of your body. Anywhere your skin needs firmness, smoothness, or hydrating repair, OS-01 BODY delivers targeted support.

        Lightweight Feel, Long-Lasting Results

        The silky, fast-absorbing texture melts into the skin without residue, making it perfect for daily use. Despite its light feel, it provides deep, long-lasting moisture and continuous barrier-strengthening benefits.

        Backed by Over 5 Years of Research

        OS-01 BODY is the result of extensive R&D, screening more than 900 peptides to find one that effectively reverses biological skin aging. Every bottle embodies years of scientific rigor and a commitment to skin longevity.

        Complements Any Skincare Routine

        Whether your routine is simple or advanced, OS-01 BODY fits seamlessly. Use it alone or layer it with your favorite body moisturizers — its peptide-driven benefits work independently to enhance your skin’s overall health.